Gut microbiome is associated with asthma and race in children with food allergy.

ABSTRACT:

Background

The composition of the gut microbiome has been associated with development of atopic conditions such as food allergy (FA) and asthma. African American or Black children with FA have higher rate of asthma compared to their White counterparts.

Objective

We sought to investigate whether the diversity and relative abundance (RA) of gut microbiota is different between children with FA from different racial backgrounds living in the same cities. Furthermore, we aimed to understand whether the difference in the gut microbiota is associated with asthma in children with FA.

Methods

We analyzed and compared the stool microbiome of a cohort of Black and White children with FA by shotgun genomic sequencing.

Results

A total of 152 children with IgE-mediated FA en

SUBMITTER: Mahdavinia M 

PROVIDER: S-EPMC10872992 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature