Obesity is associated with biliary tract cancer mortality and incidence: A pooled analysis of 21 cohort studies in the Asia Cohort Consortium.

ABSTRACT: Body fatness is considered a probable risk factor for biliary tract cancer (BTC), whereas cholelithiasis is an established factor. Nevertheless, although obesity is an established risk factor for cholelithiasis, previous studies of the association of body mass index (BMI) and BTC did not take the effect of cholelithiasis fully into account. To better understand the effect of BMI on BTC, we conducted a pooled analysis using population-based cohort studies in Asians. In total, 905 530 subjects from 21 cohort studies participating in the Asia Cohort Consortium were included. BMI was categorized into four groups: underweight (<18.5 kg/m² ); normal (18.5-22.9 kg/m² ); overweight (23-24.9 kg/m² ); and obese (25+ kg/m² ). The association between BMI and

SUBMITTER: Oze I 

PROVIDER: S-EPMC10873020 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature