Impact of mechanical power and positive end expiratory pressure on central vs. mixed oxygen and carbon dioxide related variables in a population of female piglets.

ABSTRACT:

Introduction

The use of the pulmonary artery catheter has decreased overtime; central venous blood gases are generally used in place of mixed venous samples. We want to evaluate the accuracy of oxygen and carbon dioxide related parameters from a central versus a mixed venous sample, and whether this difference is influenced by mechanical ventilation.

Materials and methods

We analyzed 78 healthy female piglets ventilated with different mechanical power.

Results

There was a significant difference in oxygen-derived parameters between samples taken from the central venous and mixed venous blood (S v¯$$ \overline{v} $$ O₂ = 74.6%, ScvO2 = 83%, p < 0.0001). Conversely, CO2-related parameters were similar, with strong correlation. Ventilation with higher mechanica

SUBMITTER: Fioccola A 

PROVIDER: S-EPMC10873162 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature