Association of Dry Eye Symptoms and Signs in Patients with Dry Eye Disease.

ABSTRACT:

Purpose

To determine the correlations among symptoms and signs of dry eye disease (DED) in the Dry Eye Assessment and Management (DREAM) study.

Methods

A total of 535 patients with moderate-to-severe DED were assessed for symptoms using the Ocular Surface Disease Index (OSDI) and four DED signs in both eyes (conjunctival lissamine green staining, corneal fluorescein staining, Schirmer's testing, and tear break-up time (TBUT)) following standardized protocols at baseline and follow-up visits (months 3, 6, and 12). Spearman correlation coefficients (rho) were calculated for correlations among symptoms and signs of DED at baseline and among changes in symptoms and signs from baseline at 12 months. The confidence intervals and p-values for correlation coefficients were calculate

SUBMITTER: Tawfik A 

PROVIDER: S-EPMC10873469 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature