Traffic-related air pollution and dementia incidence in the Adult Changes in Thought Study.

ABSTRACT:

Background

While epidemiologic evidence links higher levels of exposure to fine particulate matter (PM_2.5) to decreased cognitive function, fewer studies have investigated links with traffic-related air pollution (TRAP), and none have examined ultrafine particles (UFP, ≤100 nm) and late-life dementia incidence.

Objective

To evaluate associations between TRAP exposures (UFP, black carbon [BC], and nitrogen dioxide [NO₂]) and late-life dementia incidence.

Methods

We ascertained dementia incidence in the Seattle-based Adult Changes in Thought (ACT) prospective cohort study (beginning in 1994) and assessed ten-year average TRAP exposures for each participant based on prediction models derived from an extensive mobile monitoring campaign. We applied C

SUBMITTER: Blanco MN 

PROVIDER: S-EPMC10873482 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature