In vivo dynamic volumetric imaging of mouse testis and epididymis with optical coherence tomography†.

ABSTRACT: The implementation of live imaging in reproductive research is crucial for studying the physiological dynamics. Sperm transport is a highly dynamic process regulated by tubular contractions and luminal flows within the male reproductive tract. However, due to the lack of imaging techniques to capture these dynamics in vivo, there is little information on the physiological and biomechanical regulation of sperm transport through the male reproductive tract. Here, we present a functional in vivo imaging approach using optical coherence tomography, enabling live, label-free, depth-resolved, three-dimensional, high-resolution visualization of the mouse testis and epididymis. With this approach, we spatiotemporally captured tubular contractility in mouse testis and epididymis, as well as microst

SUBMITTER: Umezu K 

PROVIDER: S-EPMC10873499 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature