Vascular network-inspired fluidic system (VasFluidics) with spatially functionalizable membranous walls.

ABSTRACT: In vascular networks, the transport across different vessel walls regulates chemical compositions in blood over space and time. Replicating such trans-wall transport with spatial heterogeneity can empower synthetic fluidic systems to program fluid compositions spatiotemporally. However, it remains challenging as existing synthetic channel walls are typically impermeable or composed of homogeneous materials without functional heterogeneity. This work presents a vascular network-inspired fluidic system (VasFluidics), which is functionalizable for spatially different trans-wall transport. Facilitated by embedded three-dimensional (3D) printing, elastic, ultrathin, and semipermeable walls self-assemble electrostatically. Physicochemical reactions between fluids and walls are localized to vary

SUBMITTER: Yu Y 

PROVIDER: S-EPMC10873510 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature