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COVID-19 in Pediatric Patients With Acute Lymphoblastic Leukemia or Lymphoma.


ABSTRACT:

Importance

COVID-19 in pediatric patients with acute lymphoblastic leukemia or lymphoma (ALL/LLy) has not been described in detail and may affect chemotherapy administration and long-term outcomes.

Objective

To describe the clinical presentation of COVID-19 and chemotherapy modifications in pediatric patients with ALL/LLy.

Design, setting, and participants

This is a retrospective case series of patients at St Jude Children's Research Hospital and its affiliate sites with newly diagnosed ALL/LLy who were treated on the Total XVII protocol (NCT03117751) between March 30, 2020, and June 20, 2022. Participants included patients aged 1 to 18 years who were receiving protocol chemotherapy. Acute symptoms and chemotherapy modifications were evaluated for 60 days after the CO

SUBMITTER: Hashmi SK 

PROVIDER: S-EPMC10873761 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature