Perceptions and beliefs of community gatekeepers about genomic risk information in African cleft research.

ABSTRACT:

Background

A fundamental ethical issue in African genomics research is how socio-cultural factors impact perspectives, acceptance, and utility of genomic information, especially in stigmatizing conditions like orofacial clefts (OFCs). Previous research has shown that gatekeepers (e.g., religious, political, family or community leaders) wield considerable influence on the decision-making capabilities of their members, including health issues. Thus, their perspectives can inform the design of engagement strategies and increase exposure to the benefits of genomics testing/research. This is especially important for Africans underrepresented in genomic research. Our study aims to investigate the perspectives of gatekeepers concerning genomic risk information (GRI) in the presence of OFC

SUBMITTER: Oladayo AM 

PROVIDER: S-EPMC10873930 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature