Patients' awareness of recovery mediates the link between clinical and level of functional remission in schizophrenia to a larger extent in those treated with long-acting antipsychotics.

ABSTRACT:

Background

Clinical remission is a step towards functional remission for subjects with schizophrenia. While recovery is both a subjective personal journey and a clinical outcome to be targeted, data on patient self-rated outcomes are scarce.

Objectives

(i) To determine the extent to which the association between clinical and functional remission is mediated by the subjective experience of recovery as reported by patients versus their relatives or their psychiatrist and (ii) to assess differences according to treatment, specifically with oral antipsychotics only versus long-acting injectable antipsychotics (LAIs).

Design

Clinical observational study.

Methods

Community-dwelling participants with schizophrenia enrolled in the EGOFORS cohort (N

SUBMITTER: Mallet J 

PROVIDER: S-EPMC10874148 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature