Affordable blood culture systems from China: in vitro evaluation for use in resource-limited settings.

ABSTRACT:

Background

Bloodstream infections (BSI) pose a significant threat due to high mortality rates and the challenges posed by antimicrobial resistance (AMR). In 2019, an estimated 4.95 million deaths were linked to bacterial AMR. The highest impact was seen in resource-limited settings (RLS). For diagnosis of BSI, performant continuously-monitoring blood culture systems (CMBCS) have been optimized. However, in RLS, the implementation of CMBCS is hindered by budget constraints and unsuitable environmental conditions. Manufacturers from growing economies are currently producing affordable in vitro diagnostics, which could fill the gap in capacity, but so far these are not established outside their domestic markets.

Methods

This study evaluated the performance, usability, and inter

SUBMITTER: Hardy L 

PROVIDER: S-EPMC10874707 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature