Improving survival in advanced melanoma patients: a trend analysis from 2013 to 2021.

ABSTRACT:

Background

The prognosis of advanced melanoma patients has significantly improved over the years. We aimed to evaluate the survival per year of diagnosis.

Methods

All systemically treated patients diagnosed with advanced melanoma from 2013 to 2021 were included from the Dutch Melanoma Treatment Registry. Baseline characteristics and overall survival (OS) were compared between the different years of diagnosis. A multivariable Cox proportional hazards model was used to estimate the association between year of diagnosis and OS.

Findings

For this cohort study, we included 6260 systemically treated advanced melanoma patients. At baseline, there was an increase over the years in age, the percentage of patients with an ECOG PS ≥ 2, with brain metastases, and a synchronous di

SUBMITTER: van Not OJ 

PROVIDER: S-EPMC10874714 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature