Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents.

ABSTRACT: Cancer treatment remains a significant challenge due to issues such as acquired resistance to conventional therapies and the occurrence of adverse treatment-related toxicities. In recent years, researchers have turned their attention to the microbial world in search of novel and effective drugs to combat this devastating disease. Microbial derived secondary metabolites have proven to be a valuable source of biologically active compounds, which exhibit diverse functions and have demonstrated potential as treatments for various human diseases. The exploration of these compounds has provided valuable insights into their mechanisms of action against cancer cells. In-depth studies have been conducted on clinically established microbial metabolites, unraveling their anticancer properties, and sh

SUBMITTER: Giurini EF 

PROVIDER: S-EPMC10874892 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature