Transmission risk evaluation of transfusion blood containing low-density Babesia microti.

ABSTRACT:

Background

Babesia is a unique apicomplexan parasite that specifically invades and proliferates in red blood cells and can be transmitted via blood transfusion, resulting in transfusion-transmitted babesiosis. However, detecting Babesia in blood before transfusion has not received enough attention, and the risk of transfusing blood containing a low density of Babesia microti (B. microti) is unclear, possibly threatening public health and wellness.

Purpose

This study aimed to determine the lower detection limit of B. microti in blood and to evaluate the transmission risk of blood transfusion containing low-density B. microti.

Methods

Infected BALB/c mouse models were established by transfusing infected whole blood with differen

SUBMITTER: Cai Y 

PROVIDER: S-EPMC10875030 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature