Multi-level fMRI analysis applied to hemispheric specialization in the language network, functional areas, and their behavioral correlations in the ABCD sample.

ABSTRACT: Prior research suggests that the organization of the language network in the brain is left-dominant and becomes more lateralized with age and increasing language skill. The age at which specific components of the language network become adult-like varies depending on the abilities they subserve. So far, a large, developmental study has not included a language task paradigm, so we introduce a method to study resting-state laterality in the Adolescent Brain Cognitive Development (ABCD) study. Our approach mixes source timeseries between left and right homotopes of the (1) inferior frontal and (2) middle temporal gyri and (3) a region we term "Wernicke's area" near the supramarginal gyrus. Our large subset sample size of ABCD (n = 6153) allows improved reliability and validity compared to pre

SUBMITTER: Day TKM 

PROVIDER: S-EPMC10875197 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature