Association between oxidative balance score and frailty in chronic obstructive pulmonary disease.

ABSTRACT:

Background

Oxidative stress is associated with frailty and adverse outcomes in chronic obstructive pulmonary disease (COPD). The oxidative balance score (OBS) assesses oxidative stress from diet and lifestyle, with higher OBS indicating more antioxidants than oxidants. A cross-sectional study was conducted to investigate the potential association between OBS and frailty in US adults with COPD.

Methods

A total of 1201 COPD subjects from the National Health and Nutrition Examination Survey (NHANES 1999-2018) were assessed for frailty using the Frailty Index. OBS, consisting of 20 dietary and lifestyle factors, was the exposure variable. Weighted multiple logistic regression, subgroup analysis, and restricted cubic spline curves were used to assess the association between OBS a

SUBMITTER: He X 

PROVIDER: S-EPMC10875445 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature