Link between organic nanovescicles from vegetable kingdom and human cell physiology: intracellular calcium signalling.

ABSTRACT:

Background

Plant-derived nanovesicles (PDNVs) are a novelty in medical and agrifood environments, with several studies exploring their functions and potential applications. Among fruits, apples (sp. Malus domestica) have great potential as PDNVs source, given their widespread consumption, substantial waste production, and recognized health benefits. Notably, apple-derived nanovesicles (ADNVs) can interact with human cell lines, triggering anti-inflammatory and antioxidant responses. This work is dedicated to the comprehensive biochemical characterization of apple-derived nanovesicles (ADNVs) through proteomic and lipidomic analysis, and small RNAs sequencing. This research also aims to shed light on the underlying mechanism of action (MOA) when ADNVs interface with human cells, thr

SUBMITTER: Trentini M 

PROVIDER: S-EPMC10875884 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature