Hepatitis E outbreak in the health district of Bocaranga-Koui, Central African Republic, 2018-2019.

ABSTRACT:

Background

Hepatitis E virus (HEV) is a major public health disease causing large outbreaks and sporadic cases of acute hepatitis. We investigated an outbreak of HEV infection that occurred in September 2018 in the health district (HD) of Bocaranga-Koui, located in the northwestern part of Central African Republic (CAR).

Methods

Blood samples were collected from 352 patients aged 0-85 years suspected to be infected with yellow fever (YF), according to the World Health Organization YF case definition. The notification forms from recorded cases were used. Water consumed in the HD were also collected. Human samples found negative for anti-YF IgM were then tested by ELISA for anti-HEV IgM and IgG antibodies. Positive anti-HEV (IgM and/or IgG) samples and collected water were the

SUBMITTER: de Marguerite Nombot-Yazenguet MP 

PROVIDER: S-EPMC10875899 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature