Aryl hydrocarbon receptor: Linking environment to aging process in elderly patients with asthma.

ABSTRACT:

Abstract

Aging is a significant risk factor for various diseases, including asthma, and it often leads to poorer clinical outcomes, particularly in elderly individuals. It is recognized that age-related diseases are due to a time-dependent accumulation of cellular damage, resulting in a progressive decline in cellular and physiological functions and an increased susceptibility to chronic diseases. The effects of aging affect not only the elderly but also those of younger ages, posing significant challenges to global healthcare. Thus, understanding the molecular mechanisms associated with aging in different diseases is essential. One intriguing factor is the aryl hydrocarbon receptor (AhR), which serves as a cytoplasmic receptor and ligand-activated transcription factor and has been

SUBMITTER: Yang T 

PROVIDER: S-EPMC10876263 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature