Evidence integration on health damage for humidifier disinfectant exposure and legal presumption of causation.

ABSTRACT:

Objectives

Inhalation exposure to humidifier disinfectants has resulted to various types of health damages in Korea. To determine the epidemiological correlation necessary for presuming the legal causation, we aimed to develop a method to synthesize the entire evidence.

Methods

Epidemiological and toxicological studies are systematically reviewed. Target health problems are selected by criteria such as frequent complaints of claimants. Relevant epidemiologic studies are reviewed and the risk of bias and confidence level of the total evidence are evaluated. Toxicological literature reviews are conducted on three lines of evidence including hazard information, animal studies, and mechanistic studies, considering the source-to-exposure-to-outcome continuum. The confidence level

SUBMITTER: Ha M 

PROVIDER: S-EPMC10876420 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature