Risk factors for early-onset lung cancer in Korea: analysis of a nationally representative population-based cohort.

ABSTRACT:

Objectives

We examined the associations of socioeconomic factors, health behaviors, and comorbidities with early-onset lung cancer.

Methods

The study included 6,794,287 individuals aged 20-39 years who participated in a Korean national health check-up program from 2009 to 2012. During the follow-up period, 4,684 participants developed lung cancer. Multivariable Cox regression analysis was used to estimate the independent associations of potential risk factors with incident lung cancer.

Results

Older age (multivariable hazard ratio [mHR], 1.13; 95% confidence interval [CI], 1.12 to 1.14) and female sex (mHR, 1.62; 95% CI, 1.49 to 1.75) were associated with increased lung cancer risk. Current smoking was also associated with elevated risk (<10 pack-years: mHR, 1.12; 95%

SUBMITTER: Kang J 

PROVIDER: S-EPMC10876445 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature