Evaluation of therapeutic effect and prognostic value of ¹⁸F-FDG PET/CT in different treatment nodes of DLBCL patients.

ABSTRACT:

Background

In the present study, we aimed to investigate the role of baseline (B), interim (I) and end-of-treatment (Eot) ¹⁸F-FDG PET/CT in assessing the prognosis of diffuse large B cell lymphoma (DLBCL), so as to identify patients who need intensive treatment at an early stage.

Methods

A total of 127 DLBCL patients (62 men; 65 women; median age 62 years) were retrospectively analyzed in this study. Baseline (n = 127), interim (n = 127, after 3-4 cycles) and end-of-treatment (n = 53, after 6-8 cycles) PET/CT images were re-evaluated; semi-quantitative parameters such as maximum standardized uptake value of lesion-to-liver ratio (SUVmax_(LLR)) and lesion-to-mediastinum ratio (SUVmax_(LMR)), total metabolic tumor volume (TMTV) and total metaboli

SUBMITTER: Zhao W 

PROVIDER: S-EPMC10876506 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature