Prefrontal cortex structural and developmental associations with callous-unemotional traits and aggression.

ABSTRACT: Youths with high levels of callous-unemotional (CU) traits and aggression are at an increased risk for developing antisocial behaviours into adulthood. In this population, neurostructural grey matter abnormalities have been observed in the prefrontal cortex. However, the directionality of these associations is inconsistent, prompting some to suggest they may vary across development. Although similar neurodevelopmental patterns have been observed for other disorders featuring emotional and behavioural dysregulation, few studies have tested this hypothesis for CU traits, and particularly not for aggression subtypes. The current study sought to examine grey matter correlates of CU traits and aggression (including its subtypes), and then determine whether these associations varied by age. Fift

SUBMITTER: Hostetler N 

PROVIDER: S-EPMC10876571 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature