Neural correlates of home-based intervention effects on value-based sequential decision-making in healthy older adults.

ABSTRACT: Older adults demonstrate difficulties in sequential decision-making, which is partly attributed to under-recruitment of prefrontal networks. It is, therefore, important to understand the mechanisms that may improve this ability. This study investigated the effectiveness of an 18-sessions, home-based cognitive intervention and the neural mechanisms that underpin individual differences in intervention effects. Participants were required to learn sequential choices in a 3-stage Markov decision-making task that would yield the most rewards. Participants were assigned to better or worse responders group based on their performance at the last intervention session (T18). Better responders improved significantly starting from the fifth intervention session while worse responders did not improve ac

SUBMITTER: Kang K 

PROVIDER: S-EPMC10876581 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature