Script-based implementation of automatic grid placement for lattice stereotactic body radiation therapy.

ABSTRACT:

Background and purpose

Spatially fractionated radiation therapy (SFRT) has demonstrated promising clinical response in treating large tumors with heterogeneous dose distributions. Lattice stereotactic body radiation therapy (SBRT) is an SFRT technique that leverages inverse optimization to precisely localize regions of high and lose dose within disease. The aim of this study was to evaluate an automated heuristic approach to sphere placement in lattice SBRT treatment planning.

Materials and methods

A script-based algorithm for sphere placement in lattice SBRT based on rules described by protocol was implemented within a treatment planning system. The script was applied to 22 treated cases and sphere distributions were compared with manually placed spheres in terms of number

SUBMITTER: Tucker WW 

PROVIDER: S-EPMC10876586 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature