The importance of considering competing risks in recurrence analysis of intracranial meningioma.

ABSTRACT:

Background

The risk of recurrence is overestimated by the Kaplan-Meier method when competing events, such as death without recurrence, are present. Such overestimation can be avoided by using the Aalen-Johansen method, which is a direct extension of Kaplan-Meier that accounts for competing events. Meningiomas commonly occur in older individuals and have slow-growing properties, thereby warranting competing risk analysis. The extent to which competing events are considered in meningioma literature is unknown, and the consequences of using incorrect methodologies in meningioma recurrence risk analysis have not been investigated.

Methods

We surveyed articles indexed on PubMed since 2020 to assess the usage of competing risk analysis in recent meningioma literature. To compare r

SUBMITTER: Mirian C 

PROVIDER: S-EPMC10876814 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature