Prevalence and clinical significance of potential drug-drug interactions among lung transplant patients.

ABSTRACT: Background: Drug-drug interactions (DDIs) are a major but preventable cause of adverse drug reactions. There is insufficient information regarding DDIs in lung transplant recipients. Objective: This study aimed to determine the prevalence of potential DDIs (pDDIs) in intensive care unit (ICU) lung transplant recipients, identify the real DDIs and the most frequently implicated medications in this vulnerable population, and determine the risk factors associated with pDDIs. Methods: This retrospective cross-sectional study included lung transplant recipients from January 2018 to December 2021. Pertinent information was retrieved from medical records. All prescribed medications were screened for pDDIs using the Lexicomp^® drug interaction software. According to

SUBMITTER: Zhang J 

PROVIDER: S-EPMC10876870 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature