Diagnostic biomarkers for chronic rhinosinusitis in adult asthmatics in real-world practice.

ABSTRACT:

Background

Chronic rhinosinusitis (CRS) is a common comorbid condition of asthma that affects the long-term outcome of asthmatic patients. CRS is a heterogeneous disease requiring multiple biomarkers to explain its pathogenesis. This study aimed to develop potential biomarkers for predicting CRS in adult asthmatic patients in a real-world clinical setting.

Methods

This study enrolled 108 adult asthmatic patients who had maintained anti-asthmatic medications, including medium-to-high doses of inhaled corticosteroid plus long-acting β2-agonists, and compared clinical characteristics between patients with CRS (CRS group) and those without CRS (non-CRS group). CRS was diagnosed based on the results of paranasal sinus X-ray and/or osteomeatal-unit CT as well as clinical symptoms.

SUBMITTER: Jang JH 

PROVIDER: S-EPMC10877182 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature