Inflammation mediates the relationship between diet quality assessed by healthy eating index-2015 and metabolic syndrome.

ABSTRACT:

Background

Metabolic syndrome is a cluster of metabolic disorders, including obesity, hypertension, hyperglycemia, and abnormal lipid levels. However, researches on the association between overall dietary quality measured by the Healthy Eating Index-2015 (HEI-2015) and the risk of metabolic syndrome is still lacking.

Methods

This study utilized data from four cycles (2011-2018) of the National Health and Nutrition Examination Survey (NHANES) database, including 17,582 participants. Logistic regression analysis was employed to explore the correlation between HEI and the risk of metabolic syndrome. Additionally, mediation analysis was conducted to examine the effects of Systemic Immune-Inflammation Index (SII) and serum uric acid as potential mediators between HEI and metaboli

SUBMITTER: Yuguang L 

PROVIDER: S-EPMC10877714 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature