Brain reward function in people who use cannabis: a systematic review.

ABSTRACT:

Rationale

Cannabis is one of the most widely used psychoactive substances globally. Cannabis use can be associated with alterations of reward processing, including affective flattening, apathy, anhedonia, and lower sensitivity to natural rewards in conjunction with higher sensitivity to cannabis-related rewards. Such alterations have been posited to be driven by changes in underlying brain reward pathways, as per prominent neuroscientific theories of addiction. Functional neuroimaging (fMRI) studies have examined brain reward function in cannabis users via the monetary incentive delay (MID) fMRI task; however, this evidence is yet to be systematically synthesised.

Objectives

We aimed to systematically integrate the evidence on brain reward function in cannabis users examined

SUBMITTER: Beyer E 

PROVIDER: S-EPMC10877725 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature