Inflammatory markers and frailty in home-dwelling elderly, a cross-sectional study.

ABSTRACT:

Background

Low-grade, chronic inflammation during ageing, ("inflammageing"), is suggested to be involved in the development of frailty in older age. However, studies on the association between frailty, using the frailty index definition, and inflammatory markers are limited. The aim of this study was to investigate the relationship between inflammatory markers and frailty index (FI) in older, home-dwelling adults.

Method

Home-dwelling men and women aged ≥ 70 years old, living in South-East Norway were recruited and included in a cross-sectional study. The FI used in the current study was developed according to Rockwood's frailty index and included 38 variables, resulting in an FI score between 0 and 1 for each participant. Circulating inflammatory markers (IL-6, CRP, IGF-1,

SUBMITTER: Balsrud P 

PROVIDER: S-EPMC10877806 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature