Efficacy of natural products on premature ovarian failure: a systematic review and meta-analysis of preclinical studies.

ABSTRACT:

Objective

This study aims to investigate the effects of natural products on animal models of premature ovarian failure (POF).

Methods

We conducted comprehensive literature searches and identified relevant studies that examined the protective effects of natural products on experimental POF. We extracted quantitative data on various aspects such as follicular development, ovarian function, physical indicators, oxidative stress markers, inflammatory factors, and protein changes. The data was analyzed using random-effects meta-analyses, calculating pooled standardized mean differences and 95% confidence intervals. Heterogeneity was assessed using the I² statistic, and bias was estimated using the SYRCLE tool.

Results

Among the 879 reviewed records, 25 articles

SUBMITTER: Hu H 

PROVIDER: S-EPMC10877904 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature