Genomic Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2 in a County Jail.

ABSTRACT:

Background

In the coronavirus disease 2019 (COVID-19) pandemic, correctional facilities are potential hotspots for transmission. We examined the genomic epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) early in the pandemic in one of the country's largest urban jails.

Methods

Existing SARS-CoV-2 isolates from 131 detainees at the Cook County Jail in Chicago, Illinois, from March 2020 through May 2020 were analyzed by whole-genome sequencing. Contemporaneous isolates from Rush University Medical Center (Chicago, Illinois) and the Global Initiative on Sharing All Influenza Data (GISAID) were used to identify genetic clusters containing only jail isolates. Transmission windows were identified for each pair of detainees using the date of the SARS-CoV-

SUBMITTER: Adediran T 

PROVIDER: S-EPMC10878058 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature