Indication for ECMO predicts time to first actionable bleeding complication.

ABSTRACT:

Purpose

Bleeding is a major complication of patients requiring extracorporeal membrane oxygenation (ECMO). Several risk factors have been identified; however, there remains a paucity of evidence for optimal management of anticoagulation and bleeding in ECMO patients.

Methods

A total of 255 patients required ECMO from January 1996 to December 2021 at a single institution. The Bleeding Academic Research Consortium (BARC) Score was used for defining actionable bleeding. Univariate and multivariate testing were used for outcome analysis. Kaplan-Meier survival curves were plotted for time-to-event analysis.

Results

Of the 255 patients, 147 patients had no actionable bleeding complications, while 108 had at least one actionable bleeding complication. Duration of support (

SUBMITTER: Malik MI 

PROVIDER: S-EPMC10879057 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature