Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats.

ABSTRACT: Organisms must regulate their behavior flexibly in the face of environmental challenges. Failure can lead to a host of maladaptive behavioral traits associated with a range of neuropsychiatric disorders, including attention deficit hyperactivity disorder, autism, and substance use disorders. This maladaptive dysregulation of behavior is influenced by genetic and environmental factors. For example, environmental enrichment produces beneficial neurobehavioral effects in animal models of such disorders. The present study determined the effects of environmental enrichment on a range of measures related to behavioral regulation using a large cohort of male, outbred heterogeneous stock (HS) rats as subjects. Subjects were reared from late adolescence onwards either in pairs in standard housing w

SUBMITTER: Ishiwari K 

PROVIDER: S-EPMC10879139 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature