Biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation.

ABSTRACT: Artificial communication with the brain through peripheral nerve stimulation shows promising results in individuals with sensorimotor deficits. However, these efforts lack an intuitive and natural sensory experience. In this study, we design and test a biomimetic neurostimulation framework inspired by nature, capable of "writing" physiologically plausible information back into the peripheral nervous system. Starting from an in-silico model of mechanoreceptors, we develop biomimetic stimulation policies. We then experimentally assess them alongside mechanical touch and common linear neuromodulations. Neural responses resulting from biomimetic neuromodulation are consistently transmitted towards dorsal root ganglion and spinal cord of cats, and their spatio-temporal neural dynamics resemble

SUBMITTER: Valle G 

PROVIDER: S-EPMC10879152 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature