Autophagy Proteins and clinical data reveal the prognosis of polycystic ovary syndrome.

ABSTRACT:

Objective

We aimed to investigate the significance of autophagy proteins and their association with clinical data on pregnancy loss in polycystic ovary syndrome (PCOS), while also constructing predictive models.

Methods

This study was a secondary analysis. we collected endometrial samples from 33 patients with polycystic ovary syndrome (PCOS) and 7 patients with successful pregnancy control women at the Reproductive Center of the Second Hospital of Lanzhou University between September 2019 and September 2020. Liquid chromatography tandem mass spectrometry was employed to identify expressed proteins in the endometrium of 40 patients. R was use to identify differential expression proteins(DEPs). Subsequently, Metascape was utilized for Gene Ontology (GO) and Kyoto Encyclopedia

SUBMITTER: Wu Y 

PROVIDER: S-EPMC10880238 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature