Microbial profile in bile from pancreatic and extra-pancreatic biliary tract cancer.

ABSTRACT:

Background

Dysbiotic biliary bacterial profile is reported in cancer patients and is associated with survival and comorbidities, raising the question of its effect on the influence of anticancer drugs and, recently, the suggestion of perichemotherapy antibiotics in pancreatic cancer patients colonized by the Escherichia coli and Klebsiella pneumoniae.

Objective

In this study, we investigated the microbial communities that colonize tumours and which bacteria could aid in diagnosing pancreatic and biliary cancer and managing bile-colonized patients.

Methods

A retrospective study on positive bile cultures of 145 Italian patients who underwent cholangiopancreatography with PC and EPC cancer hospitalized from January 2006 to December 2020 in a QA-certified academic surgica

SUBMITTER: Di Carlo P 

PROVIDER: S-EPMC10880987 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature