Association of epicardial and intramyocardial fat with ventricular arrhythmias.

ABSTRACT:

Background

Among patients with ischemic cardiomyopathy (ICM) and nonischemic cardiomyopathy (NICM), myocardial fibrosis is associated with an increased risk for ventricular arrhythmia (VA). Growing evidence suggests that myocardial fat contributes to ventricular arrhythmogenesis. However, little is known about the volume and distribution of epicardial adipose tissue and intramyocardial fat and their relationship with VAs.

Objective

The purpose of this study was to assess the association of contrast-enhanced computed tomography (CE-CT)-derived left ventricular (LV) tissue heterogeneity, epicardial adipose tissue volume, and intramyocardial fat volume with the risk of VA in ICM and NICM patients.

Methods

Patients enrolled in the PROSE-ICD registry who underwent CE-CT we

SUBMITTER: Sani MM 

PROVIDER: S-EPMC10881203 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature