Outcomes of heart transplant recipients with prior left ventricular assist device associated stroke.

ABSTRACT:

Background

Left ventricular assist devices (LVADs) improve survival in patients with end-stage heart failure but are associated with ischemic stroke and intracranial hemorrhage (ICH). The impact of LVAD-associated stroke on transplant candidacy and outcomes has not been characterized.

Methods

Adult patients undergoing LVAD implantation at Cleveland Clinic between 2004 to 2021 were reviewed and patients who developed ischemic stroke or ICH were identified. Post-transplant survival analysis was performed between patients with LVAD-associated stroke vs. without.

Results

917 patients had an LVAD implantation of whom 244 (median age 57, 79% male) underwent subsequent transplant including 25 with prior LVAD-associated stroke. The 1- and 2-year survival after transplant in p

SUBMITTER: Shoskes A 

PROVIDER: S-EPMC10881273 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature