Converting an allocentric goal into an egocentric steering signal.

ABSTRACT: Neuronal signals that are relevant for spatial navigation have been described in many species^1-10. However, a circuit-level understanding of how such signals interact to guide navigational behaviour is lacking. Here we characterize a neuronal circuit in the Drosophila central complex that compares internally generated estimates of the heading and goal angles of the fly-both of which are encoded in world-centred (allocentric) coordinates-to generate a body-centred (egocentric) steering signal. Past work has suggested that the activity of EPG neurons represents the fly's moment-to-moment angular orientation, or heading angle, during navigation^2,11. An animal's moment-to-moment heading angle, however, is not always aligned with its goal angle-that is, the allocentric dir

SUBMITTER: Mussells Pires P 

PROVIDER: S-EPMC10881393 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature