Higher handgrip strength is linked to higher salience ventral attention functional network segregation in older adults.

ABSTRACT: Converging evidence suggests that handgrip strength is linked to cognition in older adults, and this may be subserved by shared age-related changes in brain function and structure. However, the interplay among handgrip strength, brain functional connectivity, and cognitive function remains poorly elucidated. Hence, our study sought to examine these relationships in 148 community-dwelling older adults. Specifically, we examined functional segregation, a measure of functional brain organization sensitive to ageing and cognitive decline, and its associations with handgrip strength and cognitive function. We showed that higher handgrip strength was related to better processing speed, attention, and global cognition. Further, higher handgrip strength was associated with higher segregation of th

SUBMITTER: Chong JSX 

PROVIDER: S-EPMC10881588 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature