The relationship between trajectories of renal oxygen saturation and acute kidney injury: a prospective cohort study with a secondary analysis.

ABSTRACT:

Background

Acute kidney injury (AKI) is a major postoperative consequence, affecting prognosis of older patients. Effective prediction or intervention to predict or prevent the incidence of AKI is currently unavailable.

Aims

Dynamic changes of renal tissue oxygen saturation (RSO₂) during surgery process are understudied and we intended to explore the distinct trajectories and associations with postoperative AKI.

Methods

This was a secondary analysis including data for older patients who underwent open hepatectomy surgery with informed consent. Latent class mixed models (LCMM) method was conducted to generate trajectories of intraoperative renal tissue RSO₂ through different time points. The primary outcome was postoperative 7-day AKI. The univari

SUBMITTER: Liu C 

PROVIDER: S-EPMC10881632 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature