Evaluation of a creatinine clearance correction equation based on body fat mass in older Japanese patients with diabetes.

ABSTRACT:

Background

The estimation of creatinine clearance (CCr) in older adult patients with diabetes is subject to deviations from the results of actual measurements because of changes in body composition. In the present study, we aimed to create a correction for the equation used for the estimation of CCr in older adult Asian patients with diabetes using body composition parameters.

Methods

We enrolled 50 older Japanese patients with diabetes in whom the measured values of CCr were compared with values estimated using the Cockcroft-Gault equation. The relationships between the error in the estimated CCr and body composition parameters were investigated, and the Cockcroft-Gault equation was corrected using the appropriate parameters. To evaluate the generalizability of the correcte

SUBMITTER: Utsumi S 

PROVIDER: S-EPMC10881716 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature