An ex-vivo and in-vitro dynamic simulator for surgical and transcatheter mitral valve interventions.

ABSTRACT:

Purpose

Minimally invasive mitral valve surgery (MIMVS) and transcatheter edge-to-edge repair (TEER) are complex procedures used to treat mitral valve (MV) pathologies, but with limited training opportunities available. To enable training, a realistic hemodynamic environment is needed. In this work we aimed to develop and validate a simulator that enables investigation of MV pathologies and their repair by MIMVS and TEER in a hemodynamic setting.

Methods

Different MVs were installed in the simulator, and pressure, flow, and transesophageal echocardiographic measurements were obtained. To confirm the simulator's physiological range, we first installed a biological prosthetic, a mechanical prosthetic, and a competent excised porcine MV. Subsequently, we inserted two porcine MV

SUBMITTER: Karl R 

PROVIDER: S-EPMC10881771 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature