Metabolomic profiling reveals key metabolites associated with hypertension progression.

ABSTRACT:

Introduction

Pre-hypertension is a prevalent condition among the adult population worldwide. It is characterized by asymptomatic elevations in blood pressure beyond normal levels but not yet reaching the threshold for hypertension. If left uncontrolled, pre-hypertension can progress to hypertension, thereby increasing the risk of serious complications such as heart disease, stroke, kidney damage, and others.

Objective

The precise mechanisms driving the progression of hypertension remain unknown. Thus, identifying the metabolic changes associated with this condition can provide valuable insights into potential markers or pathways implicated in the development of hypertension.

Methods

In this study, we utilized untargeted metabolomics profiling, which examines over 1,00

SUBMITTER: Al Ashmar S 

PROVIDER: S-EPMC10881871 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature