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Genetic and clinical study of myeloperoxidase's association with coronary artery disease.


ABSTRACT:

Background

Unraveling myeloperoxidase's (MPO) correlation with coronary artery disease (CAD) and genetic variations, this study seeks to enhance diagnostic precision and therapeutic strategies.

Results

CAD patients were found to be older and more male than controls. Several clinical parameters, including glucose, total bilirubin, alkaline phosphatase, creatinine, and troponin levels, showed significant variations. Moreover, CAD patients had lower red cell distribution width (RDW%) and mean platelet volume (MPV) than controls. Serum MPO levels did not differ significantly between CAD patients and controls, and no correlation was found with other clinical parameters except for glucose, creatinine, and total bilirubin.

Conclusions

The data suggest that serum MPO levels a

SUBMITTER: Adam LN 

PROVIDER: S-EPMC10881921 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature