Advanced lung cancer inflammation index predicts overall survival of hepatocellular carcinoma after hepatectomy.

ABSTRACT:

Aim

Limited data are available regarding ALI's clinical relevance and prognostic value in patients with hepatocellular carcinoma (HCC) after hepatectomy.

Materials and methods

HCC patients who received hepatectomy at the Meizhou People's Hospital from May 2011 to February 2022 were enrolled in the study cohort. The ALI was calculated as follows: ALI = BMI (kg/m²) × ALB (g/dL)/(absolute neutrophil count/absolute lymphocyte count). The primary outcome was overall survival (OS). The secondary outcome was cancer-specific survival (CSS). Univariate and multivariate Cox regression analyses were performed, followed by nomogram construction and decision curve analysis (DCA).

Results

425 HCC patients were enrolled for analyses. Lower preoperative ALI was significant

SUBMITTER: Wen YZ 

PROVIDER: S-EPMC10882069 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature