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Hydrophobicity-Based Force Field In Enzymes.


ABSTRACT: The biocatalysis process takes place with the participation of enzymes, which, depending on the reaction carried out, require, apart from the appropriate arrangement of catalytic residues, an appropriate external force field. It is generated by the protein body. The relatively small size of the part directly involved in the process itself is supported by the presence of an often complex structure of the protein body, the purpose of which is to provide an appropriate local force field, eliminating the influence of water. Very often, the large size of the enzyme is an expression of the complex form of this field. In this paper, a comparative analysis of arbitrarily selected enzymes, representatives of different enzyme classes, was carried out, focusing on the measurement of the diversity of

SUBMITTER: Roterman I 

PROVIDER: S-EPMC10882594 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature