Dielectric Detection of Single Nanoparticles Using a Microwave Resonator Integrated with a Nanopore.

ABSTRACT: The characterization of individual nanoparticles in a liquid constitutes a critical challenge for the environmental, material, and biological sciences. To detect nanoparticles, electronic approaches are especially desirable owing to their compactness and lower costs. While electronic detection in the form of resistive-pulse sensing has enabled the acquisition of geometric properties of various analytes, impedimetric measurements to obtain dielectric signatures of nanoparticles have scarcely been reported. To explore this orthogonal sensing modality, we developed an impedimetric sensor based on a microwave resonator with a nanoscale sensing gap surrounding a nanopore built on a 220 nm silicon nitride membrane. The microwave resonator has a coplanar waveguide configuration with a resonance f

SUBMITTER: Secme A 

PROVIDER: S-EPMC10882703 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature